Ursula K. Le Guin, as always, is The Stuff.
From her interview at The Paris Review:
Might that be why your fiction has been more readily admired in so-called literary circles—that it’s more engaged with human complexity and psychology?
It’s helped to make my stuff more accessible to people who don’t, as they say, read science fiction. But the prejudice against genre has been so strong until recently. It’s all changing now, which is wonderful. For most of my career, getting that label—sci-fi—slapped on you was, critically, a kiss of death. It meant you got reviewed in a little box with some cute title about Martians—or tentacles.
Also, this killed me: "My father knew Alfred Knopf personally. I’d had recorder lessons with Blanche Knopf when I was seventeen. Blanche—she was a real grande dame, oh God, she was scary. And I’d go in with my little tooter." Like, can you even PICTURE THAT? I can't.
And then later she compares genre fiction to poetry—because in both cases, you're writing within a form—and a response to that "I don’t read fiction because it isn’t real" statement and holy crow, I just want to QUOTE EVERYTHING.
So, yeah. It's an AWESOME interview, not to be missed.